Research article

Phytochemical screening and antimicrobial investigation of the ethyl acetate extract fraction of detarium microcarpum Guill and Perr. Stem bark to see its therapeutic value on bacterial microbes that will validate its folk-loric uses as remedy for children Ailment Gedigedi/Tando and also its wound healing property

Kalip Datsu Reuben^1*, Olufunke A. Sodipo², Yakubu Tarimbuka Ladi¹, Fanna Inna Abdulrahman³ and Musa DzivamaYohanna⁴

¹Department of Basic Sciences, Adamawa State College of Agriculture, P.M.B 2088, Ganye, Nigeria

²Department of Clinical Pharmacology and Therapeutics, College Of Medical Sciences, University of Maiduguri, Maiduguri, Nigeria

³Department of Chemistry, Faculty of Science, University of Maiduguri, P M B. 1069, Maiduguri, Nigeria

⁴Department of Agricultural Engineering Technology, Adamawa state College of Agriculture, P.M.B 2088, Ganye, Nigeria

Corresponding Author E-mail: datsureuben@yahoo.com

Accepted 25 February 2016

Abstract

The present study was focused to find out the phytoconstituents present in the ethyl acetate extract fraction as well as the antibacterial activities of the extract fraction of Detarium microcarpum stem bark in order to validate its folk-loric use in the treatment of the children ailment Gedigedi/Tando and its wound healing property. The phytochemical test revealed the presence of carbohydrate, tannins, cardiac glycosides, flavonoids and terpenoids. The antibacterial susceptibility test revealed broad spectrum of activity by the extract. Further studies were carried out which revealed the minimum inhibitory concentration and minimum bactericidal concentration respectively. This study thus manifested antibacterial activity that validates the use of Detarium microcarpum for wound healing and for the treatment of the children ailment Gedigedi/Tando traditionally

Keywords: Phytochemical and Antimicrobial Investigation, Ethyl acetate Extract, Detarium microcarpum, Stem Bark