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Jatropha tanjorensis
(Hospital too far) contain numerous bioactive compounds
which are greatly responsible for their pharmacological
properties. In this study, the Anti-Anaemic Potential of
Jatropha tanjorensis (Hospital too far) Leaf Extract was
compared with a Standard Blood Syrup and the Identification
of the Bioactive Compounds in the Leaf Extract was also
carried out. The leaves were air-dried and ground into
powder using a pulverizing machine, the powdered samples
were extracted using ethanol. The result of the anti-anaemic
properties of the extract showed that the haemoglobin (HB)
level ranged from
13.20±0.10 g/dl to 15.35±0.15g/dl, the packed cell volume
(PCV) ranged from 38.00±1.00% to 46.50±0.50%, the White
blood cell ranged from 3.85×109/L ±0.05 to
9.25×109/L ±0.05, the Red blood cell ranged from
5.35×1012/L ±0.15 to 5.60×1012/L
±0.10, the Platelet count ranged from 107.00×109/L
±1.00 to 365.00×109/L ±15.00.
The result of the GC-MS and FTIR characterization showed
that the following bioactive compounds were found in the
leaf;
1-propanol, Erythritol, 2-dimethyl(prop-2-enyl)
silyloxypropane, threitol, 2-o-methyl-D-mann opyranose,
2-pentadecanoic-6,10,14-trimethyl, pentadecanoic acid,
n-hexadecanoic acid, 9-octadecenoic acid, phytol,
11-octadecenoic acid, oleic acid, methyl stearate and methyl
20-methyl-heneicosanoate which appears at different peaks
from their FTIR spectrum. However, the bioactive compounds
present in the plant has been found from literatures to be
responsible for the following pharmacological properties;
antibacterial, antifungal, antidiuretic, antimalaria,
antiasthma, anticancer, cholinomimetic, antiarrhythmic,
analgesic, antihperglycemic etc
Keywords: Bioactive compounds, anti-anaemic, pharmacological
properties, characterization
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